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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM3 All Species: 37.88
Human Site: S182 Identified Species: 69.44
UniProt: Q14832 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14832 NP_000831.2 879 98879 S182 S A K L S D K S R Y D Y F A R
Chimpanzee Pan troglodytes A3QNZ8 839 95029 V175 G D E L R D K V R F P A L L R
Rhesus Macaque Macaca mulatta XP_001107588 879 98905 S182 S A K L S D K S R Y D Y F A R
Dog Lupus familis XP_541867 872 95696 S176 S A K L S D K S R Y D Y F A R
Cat Felis silvestris
Mouse Mus musculus Q9QYS2 879 99096 S182 S A K L S D K S R Y D Y F A R
Rat Rattus norvegicus P31422 879 98942 S182 S A K L S D K S R Y D Y F A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515487 775 87278 E127 E T G I E A F E Q E A R H R N
Chicken Gallus gallus XP_416842 879 98936 S182 S A K L S D K S R Y D Y F A R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 S181 A T I L S D K S R F P A F M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 T189 A K T L S D K T R F D L F A R
Honey Bee Apis mellifera NP_001011624 933 103448 T200 A K A L S D K T R F D Y F A R
Nematode Worm Caenorhab. elegans Q09630 999 113258 N233 N A D L S D K N R F E Y F A R
Sea Urchin Strong. purpuratus XP_784936 1474 165598 S750 S A R L S D K S R F E F F A R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.9 99.5 68.7 N.A. 96.6 96.5 N.A. 79.1 91 N.A. 26.5 N.A. 46 48.2 39.4 33.3
Protein Similarity: 100 45.3 99.6 82.3 N.A. 98.7 98.5 N.A. 83.8 95.4 N.A. 46 N.A. 61.6 64.7 57.1 44.9
P-Site Identity: 100 33.3 100 100 N.A. 100 100 N.A. 0 100 N.A. 53.3 N.A. 60 66.6 66.6 73.3
P-Site Similarity: 100 46.6 100 100 N.A. 100 100 N.A. 13.3 100 N.A. 66.6 N.A. 80 86.6 93.3 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 62 8 0 0 8 0 0 0 0 8 16 0 77 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 93 0 0 0 0 62 0 0 0 0 % D
% Glu: 8 0 8 0 8 0 0 8 0 8 16 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 47 0 8 85 0 0 % F
% Gly: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 16 47 0 0 0 93 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 93 0 0 0 0 0 0 0 8 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 8 0 0 0 93 0 0 8 0 8 93 % R
% Ser: 54 0 0 0 85 0 0 62 0 0 0 0 0 0 0 % S
% Thr: 0 16 8 0 0 0 0 16 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 47 0 62 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _